Pierre Robin Syndrome (PRS) (Pierre Robin Sequence, Pierre Robin Malformation, or Pierre Robin Anomaly) observable characteristics:
- Micrognathia – underdeveloped lower jaw – mandible)
- Glossoptosis – a tongue that is placed further back in the mouth
- Cleft palate – incomplete closure of the roof of the mouth, usually U-shaped closure, is present in the majority of patients
- Upper airway obstruction
PRS is a “sequence” because one of its features, micrognathia (small mandible), sets off a sequence of events before birth that cause the other signs (glossoptosis, cleft palate) and symptoms (airway obstruction) to appear.